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The effectiveness of the flu vaccine depends on the match between the flu vaccine and the types of flu viruses that are circulating. If there is a good match, the flu vaccine is usually over 60% effective in healthy adults. Flu vaccine is generally somewhat less effective in elderly persons and very young children, but vaccination can still prevent serious complications. The flu vaccine is more effective in healthy people, and it is important for healthy people to receive the flu shot to protect people close to them who may not be healthy.